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PROGRAM

DAY 1

SHORT COURSE

08:00-09:00

SHORT COURSE - 1: Guidelines for diagnosis, treatment, and epidemiological surveillance of schistosomiasis within the health services system: Diagnosis and treatment – Carlos Graeff-Teixeira (PUCRS, Brazil)

SHORT COURSE - 2: Bioinformatic tools – Juliana Assis e Gabriel Fernandes (IRR/Fiocruz, Brazil)

CONFERENCE (1 and 2)

09:00-09:30

C1: Ministry of Health Plan for Schistosomiasis Elimination in Brazil – Jeann Marie Marcelino (CGHDE/SVS/MS, Brazil)

Chair: Naftale Katz (IRR/Fiocruz, Brazil)

09:30-10:00

C2: Fiocruz Translational Program on Schistosomiasis: past, present and future – Roberto Sena Rocha (IRR/Fiocruz, Brazil)

Chair: Wim Degrave (VPPCB/Fiocruz, Brazil)

BREAK (10:00-10:20)

ROUNDTABLE (1 and 2)

10:20-12:00

RT1: Global and multi-country initiatives for schistosomiasis elimination

Coordinator: Amadou Garba (NTD/WHO/CH)

  • Global Schistosomiasis Alliance (GSA) – Jutta Reinhard-Rupp (Merck Global Health Institute)
  • COUNTDOWN – J. Russell Stothard (Liverpool School of Tropical Medicine, UK)
  • Schistosomiasis Control Initiative (SCI) – Fiona Fleming (Imperial College, UK)
  • Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) - Daniel Colley (University of Georgia, USA)

RT2: Vaccines and therapeutic targets for schistosomiasis control

Coordinator: José Mauro Peralta (UFRJ, Brazil)

  • Identification of new targets and anti-schistosomiasis vaccine formulations – Cristina Toscano (IRR/Fiocruz, Brazil)
  • TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis – Jeffrey M Bethony (George Washington University, USA)
  • Drug screening platform - Conor Caffrey (University of California San Diego, USA)
  • Searching for new antischistosomal therapeutic options by combining phenotypic and target-based approaches – Floriano Paes Silva Jr (IOC/Fiocruz, Brazil)
LUNCH (12:00-13:30)

ORAL PRESENTATIONS (1 and 2)

13:30-15:00

OP1: Epidemiology, Control, and Health Education

Coordinator: Martin J. Enk (IEC/SVS/MS ,Brazil)

OP2: Immunopathology, Molecular Biology, and Biochemistry

Coordinator: Ricardo Riccio (IGM/Fiocruz, Brazil)

BREAK (15:00-15:20)

ROUNDTABLE (3 and 4)

15:20-17:00

RT3: Parasite – Human-host Interaction

Coordinator: José Roberto Machado e Silva (UERJ, Brazil)

  • Immunomodulatory proteins and their role in parasite survival - Sérgio Costa Oliveira (ICB/UFMG, Brazil)
  • The use of interference RNA technology to understand the role of parasite proteins in their development and survival - Marina Mourão (IRR/Fiocruz, Brazil)
  • Understanding the roles of Immunoglobulin E (IgE) in human resistance to infection with Schistosoma sp. - Franco Falcone (Nottingham University, UK)
  • Interleukin-4-inducing principle from schistosome eggs (IPSE) Immunomodulatory effects - Michael Hsieh, (George Washington University, USA)

RT4: WASH and IEC strategies for schistosomiasis control/elimination

Coordinator: Andrea Gazzinelli (UFMG, Brazil)

  • Distance Learning Course: Schistosomiasis - clinical and epidemiological management in Primary Health Care – Constança Barbosa (IAM/Fiocruz, Brazil)
  • Health Education for health promotion and prevention of schistosomiasis – Maria Flávia Gazzinelli (UFMG, Brazil)
  • WASH – Current highlights in Africa - Fiona Fleming (Schistosomiasis Control Initiative, IC, UK)
  • Promotion of sustainable and healthy territories: the experience of ecological sanitation in Bocaina, Brazil - Edmundo Gallo (OTSS/Fiocruz, Brazil)

OPENING CEREMONY

17:00-18:00

Nisia Trindade Lima (President of Fiocruz)

Rodrigo Correa de Oliveira (VPPCB/Fiocruz, Brazil - Vice President of Research and Biological Collections; Program of Translational Research Fiocruz)

Roberto Sena Rocha (Coordinator of the Fiocruz Translational Program on Schistosomiasis - Fio-Schisto/PIDE)

Tereza Cristina Favre (President of the 15th International Symposium on Schistosomiasis)

Naftale Katz (Honorary President of 15th International Symposium on Schistosomiasis)

André Luiz de Abreu (Director of the Department of Surveillance of Communicable Diseases of the Secretariat of Health Surveillance, Ministry of Health)

Amadou Garba (WHO representative, NTD, CH)

Santiago Nicholls (PAHO Representative, USA)

KEYNOTE CONFERENCE

18:00-18:30

C3: WHO recommendations on achieving elimination of schistosomiasis - Amadou Garba, Schistosomiasis Control Programme, WHO Department of Control of Neglected Tropical Diseases (NTD, CH)

Chair: Rodrigo Correa de Oliveira (VPPCB/Fiocruz, Brazil)

DAY 2

SHORT COURSE

08:00-09:00

SHORT COURSE - 1: Guidelines for diagnosis, treatment, and epidemiological surveillance of schistosomiasis within the health services system: Malacological surveillance - Silvana Thiengo (IOC/Fiocruz, Brazil)

SHORT COURSE - 2: Bioinformatic tools – Juliana Assis e Gabriel Fernandes (IRR/Fiocruz, Brazil)

CONFERENCE (4 and 5)

09:00-09:30

C4: Delivering integrated health solutions to fight schistosomiasis - Jutta Reinhard-Rupp and Beatrice Greco (Merck Global Health Institute, CH)

Chair: L.A. Tchuem Tchuenté (CSP, CM)

09:30-10:00

C5: Water and basic sanitation for health promotion and prevention of neglected diseases - Léo Heller (IRR/Fiocruz, Brazil)

Chair: Constança Simões Barbosa (IAM/Fiocruz, Brazil)

BREAK (10:00-10:20)

ROUNDTABLE (5 and 6)

10:20-12:00

RT5: Schistosomiasis in pre-school age children

Coordinator: Amaya Bustinduy (LSHTM, UK)

  • Schisto in PSAC (Africa), Epidemiology, available clinical/safety data on treatment with PZQ, and recent WHO recommendations – Takafira Mduluza (University of Zimbabwe, SW)
  • Process development and manufacturing of pediatric PZQ ODT formulation – role of Farmanguinhos –  Daniel Lacerda (Farmanguinhos, Fiocruz, Brazil)
  • From clinical development of pediatric PZQ ODT to approval and access –  Elly Kourany-Lefoll (Global Program Lead, PEDPZQ Consortium, CH)

RT6: Epidemiology and control

Coordinator: Otavio Pieri (IOC/Fiocruz, Brazil)

  • Analysis of impact of mass drug administration for the control of schistosomiasis in hyperendemic areas of the State of Pernambuco, Brazil - José Alexandre M. da Silva (Nova University of Lisbon, PT)
  • Moving towards the elimination of schistosomiasis in Sub-Saharan Africa: the PHASE initiative - L.A. Tchuem Tchuenté (Centre for Schistosomiasis & Parasitology, Cameroon, CM)
  • Schistosomiasis and soil-transmitted helminthiases in the Americas: analysis of the current situation – Santiago Nicholls (Regional Neglected Infectious Diseases Advisor, PAHO, USA)
LUNCH (12:00-13:30)

ORAL PRESENTATIONS (3 and 4)

13:30-15:00

Intermediate hosts

Coordinator: Cristiane Lafetá F. Mendonça (IRR/Fiocruz, Brazil)

Diagnosis, Treatment, and Clinical aspects

Coordinator: Marta Cavalcanti (UFRJ, Brazil)

BREAK (15:00-15:20)

ROUNDTABLE (7 and 8)

15:20-17:00

RT7: New trends on the intermediate host

Coordinator: Silvana Carvalho Thiengo (IOC/Fiocruz, Brazil)

  • Brazil's contribution to the characterization of the genome of Biomphalaria – Roberta Caldeira (IRR/Fiocruz, Brazil)
  • New approaches to the study of snails involved in schistosomiasis transmission – Eric S. Loker (University of New Mexico, USA)
  • New strategies for snail control and surveillance – Moses Chimbari (University of Kwazulu-Natal, South Africa)
  • Integrated transcriptomics, proteomics and ultrastructural analysis to evaluate the schistosomastatic effect of a natural molluscicide - Ronaldo C. Augusto (University of Perpignan, France)

RT8: Diagnostic tools in post-elimination settings

Coordinator: Fernando Bezerra (UFCE, Brazil)

  • The use of Helmintex test for monitoring interruption of schistosomiasis transmission- Carlos Graeff-Teixeira (PUCRS, Brazil)
  • Enhancing the CAA Assay for Diagnosis of Schistosomiasis - Govert van Dam and Paul Corstjens (LUMC, University of Leiden, NL)
  • Challenges of diagnosing schistosomiasis in patients with low parasite load – Paulo Marcos Z. Coelho (IRR/Fiocruz, Brazil)

CONFERENCE 6

17:00-17:30

C6: Whole genome analysis of a schistosomiasis-transmitting freshwater snail - Coen M. Adema (University of New Mexico, USA)

Chair: Roberta Caldeira (IRR/Fiocruz, Brazil)

17:30-18:30

POSTER SESSION

DAY 3

SHORT COURSE

08:00-09:00

SHORT COURSE - 1: Guidelines for diagnosis, treatment, and epidemiological surveillance of schistosomiasis within the health services system: Epidemiological surveillance - Jeann Marie Marcelino (CGHDE/SVS/MS, BRAZIL)

SHORT COURSE - 2: Bioinformatic tools – Juliana Assis e Gabriel Fernandes (IRR/Fiocruz, Brazil)

CONFERENCE (7 and 8)

09:00-09:30

C7: New guidelines for schistosomiasis elimination based on more sensitive diagnosis assays – Daniel Colley, (University of Georgia, USA)

Chair: Mitermayer Reis (IGM/Fiocruz, Brazil)

09:30-10:00

C8: Moving beyond morbidity control toward elimination of transmission - Charles King (Case Western Reserve University, USA)

Chair: J. Russell Stothard (LSTM, UK)

BREAK (10:00-10:20)

ROUNDTABLE (9 and 10)

10:20-12:00

RT9: Persisting schistosomiasis transmission

Coordinator: Carlos Eduardo Grault (ENSP/Fiocruz, Brazil)

  • High-risk tourism in vulnerable areas – Constança Barbosa (IAM/Fiocruz, Brazil)
  • Effect of recurrent treatment in areas of persisting transmission – Ronald Blanton (Case Western Reserve University, USA)
  • Schistosomiasis outbreak in Lençois, Bahia – Marta Lima (GT-PCE/SESAB, Brazil)
  • Schistosomiasis in the Amazon region – Martin J. Enk (IEC/SVS/MS, Brazil)

RT10: Clinical and Pathological aspects

Coordinator: Marcelo Pelajo (IOC/Fiocruz, Brazil)

  • Chronic and severe schistosomiasis: the experience of the decentralized care reference network in the state of Pernambuco, Brazil – Ana Lúcia Coutinho Domingues (UFPE, Brazil)
  • Female Genital Schistosomiasis (FGS) as a risk factor for HIV - Amaya Bustinduy (LSHTM, UK)
  • New trends in ultrasound assessment of Schistosomiasis Mansoni - Joachim Ritcher (Institute of Tropical Medicine, Charité University Berlin, Germany)
  • Pathogenesis of schistosomiasis fibrosis – Thiago Almeida Pereira (Stanford University School of Medicine, USA)

CLOSING CEREMONY

12:00-13:00

Awards of best Dissertation and Thesis in schistosomiasis

Rodrigo Correa de Oliveira (Vice-President of Research - Fiocruz)

Roberto Sena Rocha (Coordinator of the Fiocruz Translational Program on Schistosomiasis - Fio-Schisto/PIDE)

Tereza Favre (President of the 15th International Symposium on Schistosomiasis)